Maceneolignan H

• UNSPSC Description:

  Maceneolignan H (Compound 8) is a neolignane compound isolated from the arils of Myristica fragrans. Maceneolignan H is a selective CCR3 antagonist (EC50 = 1.4 μM). Maceneolignan H has the potential for the research of allergic diseases[1].

• Target Antigen:

  CCR

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/maceneolignan-h.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H]([C@@H](C(C=C1)=CC(OC)=C1OC)OC(C)=O)OC(C(OC)=CC(CC=C)=C2)=C2OC

• Molecular Weight:

  430.49

• References & Citations:

  [1]Morikawa T, et al. Neolignans from the Arils of Myristica fragrans as Potent Antagonists of CC Chemokine Receptor 3. J Nat Prod. 2016;79(8):2005-2013.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1314042-85-7