IdeS, Streptococcus pyogenes

• Description:

  IdeS Protein is a highly specific IgG endopeptidase evolved from Streptococcus pyogenes, which can degrade IgG and participate in the immune response. IdeS Protein inhibits the function of certain neutrophil effectors, namely the production of reactive oxygen species (ROS), independently of IgG endopeptidase activity. ideS Protein, Streptococcus pyogenes (Active) is the recombinant ideS, expressed by E. coli, with tag-free.

• Product Name Alternative:

  IdeS Protein, Streptococcus pyogenes (Active), Others, E. coli

• UNSPSC:

  12352202

• Type:

  Reference compound

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/ides-protein-streptococcus-pyogenes-active.html

• Molecular Formula:

  / (Gene_ID) F8V4V0 (D30-N341) (Accession)

• Molecular Weight:

  Approximately 35.4 kDa

• References & Citations:

  [1]von Pawel-Rammingen U. Streptococcal IdeS and its impact on immune response and inflammation. J Innate Immun. 2012;4 (2) :132-40.|[2]Shin JI, et al. Anti-glomerular basement membrane disease (Goodpasture disease) : From pathogenesis to plasma exchange to IdeS. Ther Apher Dial. 2022 Feb;26 (1) :24-31.

• Shipping Conditions:

  Dry ice.

• Scientific Category:

  Recombinant Proteins