11-Hydroxycanthin-6-one

11-Hydroxycanthin-6-one

• CAS Number: 75969-83-4
• UNSPSC Description: 11-Hydroxycanthin-6-one, a canthin-6-one alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/11-hydroxycanthin-6-one.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4O)C=C1
• Molecular Weight: 236.23
• References & Citations: [1]Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3.|[2]Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5(1):17-22.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported