CM-272

CAT: 0026-B3250-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B3250-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CM-272 is a potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death. Displays anti-tumor activity.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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