AN-2728

CAT: 0026-B2220-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2220-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AN-2728 is a boron-based, topical anti-inflammatory agent that acts as a phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.11 µM). It is less potent against PDE1A, PDE3A, and PDE7A (IC₅₀s = 6.12, 6.41, and 0.73 µM, respectively). AN-2728 suppresses the release of the proinflammatory cytokines TNF-α, IL-2, INF-γ, IL-5, and IL-10 with IC₅₀ values of 0.50, 0.59, 0.72, 2.25, and 2.58 µM, respectively.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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