1alpha-Hydroxy VD4

1alpha-Hydroxy VD4

• Product Name Alternative: 1α-Hydroxy vitamin D4
• CAS Number: 143032-85-3
• UNSPSC Description: 1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value； Target: VD analog
• Target Antigen: VD/VDR
• Type: Reference compound
• Related Pathways: Vitamin D Related/Nuclear Receptor
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1alpha-hydroxy-vd4.html
• Purity: 98.41
• Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2[C@@](CC[C@@H]3[C@H](C)CC[C@H](C)C(C)C)([H])[C@]3(C)CCC/2
• Molecular Weight: 414.66
• References & Citations: [1]M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported