MMP-2/MMP-9-IN-1

MMP-2/MMP-9-IN-1

• CAS Number: 193807-58-8
• UNSPSC Description: MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mmp-2-mmp-9-in-1.html
• Purity: 99.25
• Solubility: 10 mM in DMSO
• Smiles: OC([C@@H](CC1=CC=CC=C1)NS(C2=CC=C(C3=CC=CC=C3)C=C2)(=O)=O)=O
• Molecular Weight: 381.44
• References & Citations: [1]Y Tamura, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported