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Narasin

CAT: 0026-B3020-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B3020-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Narasin is an ionophore antibiotic which is a derivative of salinomycin. It modifies the permeability of cellular membranes to cationic metal species. It inhibits NF-κB signaling via inhibition of IκBα phosphorylation with an IC₅₀ of 3.2 µM. Treatment with narasin (2-4 µM) and TRAIL synergistically induces apoptosis in human glioma cells by inducing ER stress and CHOP upregulation.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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