Products for Research Use Only
RegisterLogin

Narasin

CAT: 0804-HY-121410-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121410-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Narasin is a cationic ionophore antibiotic and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin has antimicrobial, antiviral anticancer activity. Narasin inhibits tumor metastasis and growth of ERα‑positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL‑6/STAT3 signaling pathways[1][2][3].
CAS Number
55134-13-9
UNSPSC
12352005
Hazard Statement
H300
Target
Antibiotic; Apoptosis; Bacterial; NF-κB; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/narasin.html
Purity
98.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@]2(O[C@](C)([C@]3([H])O[C@H]([C@](CC)(O)CC3)C)CC2)O[C@@]4(O[C@]([C@@H](C)C[C@H]4C)([H])[C@@H](CC)C([C@@H](C)[C@@H](O)[C@@H]([C@]5([H])O[C@@]([C@@H](C)C[C@@H]5C)([H])[C@@H](CC)C(O)=O)C)=O)C=C1
Molecular Formula
C43H72O11
Molecular Weight
765.03
Precautions
H300
References & Citations
[1]Ghada Bouguerra, et al. Stimulation of Eryptosis by Narasin. Cell Physiol Biochem. 2015;37 (5) :1807-16.|[2]Low JS, et al. Narasin, a novel antiviral compound that blocks dengue virus protein expression. Antivir Ther. 2011;16 (8) :1203-18.|[3]Chen J, et al. Narasin inhibits tumor metastasis and growth of ERα‑positive breast cancer cells by inactivation of the TGF‑β/SMAD3 and IL‑6/STAT3 signaling pathways. Mol Med Rep. 2020 Dec;22 (6) :5113-5124.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Coccidia

Alternative Products

CatalogName
BA1089-1Narasin
N033-5MGNarasin sodium
C3061-5Narasin (sodium salt)

Popular Products