Narasin (sodium)

CAT: 0804-HY-112225-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112225-01Size:1 mg
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Description
Narasin sodium is a cationic ionophore and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin sodium has antimicrobial and anticancer activity[1].
CAS Number
[58331-17-2]
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Apoptosis; Bacterial; NF-κB; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/narasin-sodium.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@]2(O[C@](C)([C@]3([H])O[C@H]([C@](CC)(O)CC3)C)CC2)O[C@@]4(O[C@]([C@@H](C)C[C@H]4C)([H])[C@@H](CC)C([C@@H](C)[C@@H](O)[C@@H]([C@]5([H])O[C@@]([C@@H](C)C[C@@H]5C)([H])[C@@H](CC)C(O[Na])=O)C)=O)C=C1
Molecular Formula
C43H71NaO11
Molecular Weight
787.01
Precautions
P264-P270-P330-P501
References & Citations
[1]Miller SC, et al. Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. Biochem Pharmacol. 2010 May 1;79 (9) :1272-80.|[2]Ghada Bouguerra, et al. Stimulation of Eryptosis by Narasin. Cell Physiol Biochem. 2015;37 (5) :1807-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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