27-Hydroxycholesterol

CAT: 0026-B2988-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2988-5Size:5 mg
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Description
27-Hydroxycholesterol is a hydroxylation product of cholesterol which is produced by the activity of the enzyme sterol 27-hydroxylase. It activates LXRα and LXRβ in vitro with EC₅₀ values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. The levels of 27-hydroxycholesterol are elevated in patients with Alzheimer's disease and mild cognitive impairment.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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