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R-59-022

CAT: 0026-B2975-1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-B2975-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R-59-022 is an inhibitor of Diacylglycerol (DAG) kinase with an IC₅₀ of 2.8 µM. The inhibition of Diacylglycerol kinase results in increased DAG-dependent protein kinase C (PKC) activity and potentiates aggregation of thrombin-stimulated platelets. R59022 inhibits thromboxane A(2) analogue U46619-induced contractions in mouse aorta and porcine coronary artery at concentrations of 0.1 μM to 30 μM. R-59-022 (10 µM) induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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Alternative Products

CatalogName
T16709-01R 59-022
T72322-01R 59-022 hydrochloride
HY-107613A-01R 59-022 (hydrochloride)
HY-107613R-01R 59-022 (Standard)
256394-01R 59-022 discontinued. See 463438
TRC-R020000-1GR-59-022 (Diacylglycerol Kinase Inhibitor I)
463439R-59-022-d5 (Mono-defluoro Ritanserin-d5)
257145-01YM 022
532982YM-022
HY-159130-01AO-022

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