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PTGS2 Antibody

CAT: 0013-GTR18187328Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18187328Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cox2 antibody
Product Name Alternative
Rabbit anti-COX2 antibody, Prostaglandin G/H synthase 2 antibody, Cyclooxygenase-2 antibody, Prostaglandin-endoperoxide synthase 2 antibody, Prostaglandin H2 synthase 2 antibody, PGH synthase 2 antibody, PGHS-2 antibody
UniProt
P35354
Reactivity
Human, Mouse, Rat
Immunogen
This whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
Target
PTGS2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Concentration
55 mg/mL
Dilution
ELISA: 1:10,000 - 1:50,000, WB: 1:5,000 - 1:10,000
Purity
This antiserum is directed against human Cox-2. Two different isoforms of the enzyme are known, Cox-1 and Cox-2. A BLAST analysis was used to suggest cross-reactivity with Cox-2 in human, mouse and rat based on a homology with the immunizing sequence and should not cross react with Cox-1. Reactivity against homologues from other sources is not known. Reactivity of this antibody with Cox-2 from other species is unknown.
Form
Liquid (sterile filtered)
Storage Conditions
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Notes
For research use only.
Applications Notes
Cox-2 (Cyclooxygenase-2) is an inducible enzyme that is normally absent from cells, however, in response to growth factors, tumor promoters and some cytokines, it undergoes a rapid and transient expression. This antiserum against Human Cox-2 and has been tested for use in immunoblotting. The antibody recognizes Cox-2 at 70kDa in Sf9 cell lines transfected with Cox-2 as well as in WISH cells induced with IL-1b. Reactivity in other immunoassays is unknown.
Tested Applications
ELISA, WB
NCBI Accession Number
NP_000954.1
Host or Source
Rabbit
Preservative
0.01% (w/v) Sodium Azide
Isotype
Antiserum

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