Products for Research Use Only
RegisterLogin

COX2 Antibody / PTGS2

CAT: 0013-GTR18082767-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18082767-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA) . Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS) . Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90% of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
UniProt
P35354
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 442-572) was used as the immunogen for the COX2 antibody.
Clonality
Monoclonal
Clone
COX2/1941
Conjugation
Unconjugated
Field of Research
Cancer Biology; Metabolism Research
Purification
Protein G affinity chromatography
Dilution
ELISA (order BSA-free format for coating), Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the COX2 antibody should be determined by the researcher.
Tested Applications
ELISA, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2b, kappa

Related Products

CatalogName
GTR17696561COX2/PTGS2 Antibody
GTR18224218PTGS2/COX2/COX-2 Antibody
GTR18221743PTGS2/COX2/COX-2 Antibody
GTR18221744PTGS2/COX2/COX-2 Antibody
GTR18039770-01COX2/PTGS2 polyclonal antibody
GTR18987294COX2 / PTGS2 Immunizing Peptide
GTR18317066COX2 Antibody / Cyclooxygenase 2 / PTGS2
GTR17693274Cox2 PTGS2 Rabbit Monoclonal Antibody
GTR17692144COX2 PTGS2 Rabbit Monoclonal Antibody
GTR18317067-01COX2 Antibody / Cyclooxygenase 2 / PTGS2

Alternative Products

CatalogName
V8038-20UGCOX2 Antibody / PTGS2
R32712PTGS2 Antibody / COX2
V8039-20UGRecombinant COX2 Antibody / PTGS2
STJ70106Anti-COX2 / PTGS2 antibody
BS70317COX2/PTGS2 polyclonal antibody
F54601-0.4MLCyclooxygenase 2 Antibody / COX2 / PTGS2
V4766-100UGCOX2 Antibody / Cyclooxygenase 2 / PTGS2
GT15206-100COX2 (PTGS2) goat polyclonal antibody
RA18005-100COX2 (PTGS2) rabbit polyclonal antibody
MBS421257-01Goat anti-COX2/PTGS2 Antibody

Popular Products