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Sulfapyridine (Standard)

CAT: 0804-HY-B0212R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0212R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulfapyridine (Standard) is the analytical standard of Sulfapyridine. This product is intended for research and analytical applications. Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities[1][2][3].
CAS Number
144-83-2
UNSPSC
12352005
Hazard Statement
H361
Target
Antibiotic; Bacterial; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sulfapyridine-standard.html
Purity
99.86
Solubility
H2O : < 0.1 mg/mL
Smiles
O=S(C1=CC=C(N)C=C1)(NC2=NC=CC=C2)=O
Molecular Formula
C11H11N3O2S
Molecular Weight
249.29
Precautions
H361
References & Citations
[1]Kazuki Omoteyama, et al. Effects of salazosulfapyridine on the profile of cell surface proteins, revealed by biotinylation of cell surface proteins and 2-dimentional electrophoresis. Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867 (1) :47-56.|[2]J J Andreasen, et al. In vitro susceptibility of diarrhoea producing gram negative enteric bacteria to sulfasalazine, 5-aminosalicylic acid, sulfapyridine and four quinolones. Brief report. APMIS. 1988 Jun;96 (6) :568-70.|[3]Y L Hong, et al. Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39 (8) :1756-63.|[4]H M Kim, et al. Inhibitory effect of mast cell-mediated immediate-type allergic reactions by sulfapyridine. Immunopharmacol Immunotoxicol. 2000 May;22 (2) :253-66.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

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