MF-438

CAT: 0804-HY-15822-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15822-01Size:1 mg
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Description
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1[1].
CAS Number
[921605-87-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Stearoyl-CoA Desaturase (SCD)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mf-438.html
Purity
99.92
Solubility
DMF : 50 mg/mL (ultrasonic) |DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(C1=CC=CC=C1OC2CCN(C3=NN=C(C4=NN=C(C)S4)C=C3)CC2)(F)F
Molecular Formula
C19H18F3N5OS
Molecular Weight
421.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438) . Bioorg Med Chem Lett. 2010 Jan 15;20 (2) :499-502.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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