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L-Penicillamine

CAT: 0804-HY-116073-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116073-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength[1][2].
CAS Number
1113-41-3
UNSPSC
12352209
Hazard Statement
H315, H319, H372, H413
Target
Biochemical Assay Reagents
Type
Peptides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-penicillamine.html
Purity
97.0
Solubility
H2O : 33.33 mg/mL (ultrasonic)
Smiles
N[C@H](C(O)=O)C(S)(C)C
Molecular Formula
C5H11NO2S
Molecular Weight
149.22
Precautions
H315, H319, H372, H413
References & Citations
[1]Jonathan Lowther, et al. L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. Med. Chem. Commun., 2012,3, 1003-1008.|[2]Roland Degenkolbe, et al. Chelating agents stabilize the monomeric state of the zinc binding human papillomavirus 16 E6 oncoprotein. Biochemistry. 2003 Apr 8;42 (13) :3868-73.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Peptides
Clinical Information
No Development Reported