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Penicillamine-d3

CAT: 0804-HY-B0300SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0300SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Penicillamine-d3 is the deuterium labeled Penicillamine. Penicillamine (D- (-) -Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
CAS Number
2925655-01-0
Product Name Alternative
D- (-) -Penicillamine-d3
UNSPSC
12352211
Target
Cuproptosis; Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
N[C@H](C(C)(S)C([2H])([2H])[2H])C(O)=O
Molecular Formula
C5H8D3NO2S
Molecular Weight
152.23
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Peisach, J. and W.E. Blumberg, A mechanism for the action of penicillamine in the treatment of Wilson's disease. Mol Pharmacol, 1969. 5 (2) : p. 200-9.|[3]Jaffe, I.A., K. Altman, and P. Merryman, The Antipyridoxine Effect of Penicillamine in Man. J Clin Invest, 1964. 43: p. 1869-73.|[4]Camp, A.V., Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med, 1977. 70 (2) : p. 67-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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