p38 alpha/MAPK14 + p38 beta/MAPK11 + p38 gamma/MAPK12 Recombinant Rabbit Monoclonal Antibody [PSH03-60]

p38 alpha/MAPK14 + p38 beta/MAPK11 + p38 gamma/MAPK12 Recombinant Rabbit Monoclonal Antibody [PSH03-60]

• Description: A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a serine/threonine-specific protein kinase). MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. MAP kinases are found in eukaryotes only, but they are fairly diverse and encountered in all animals, fungi and plants, and even in an array of unicellular eukaryotes. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. The closest relatives of MAPKs are the cyclin-dependent kinases (CDKs).
• Product Name Alternative: ERK 6 antibody ERK-6 antibody ERK6 antibody Extracellular signal-regulated kinase 6 antibody MAP kinase 12 antibody MAP kinase p38 gamma antibody MAPK 12 antibody Mapk12 antibody Mitogen Activated Protein Kinase 12 antibody Mitogen activated protein kinase p38 gamma antibody Mitogen-activated protein kinase 12 antibody Mitogen-activated protein kinase p38 gamma antibody MK12_HUMAN antibody P38 GAMMA antibody P38GAMMA antibody PRKM12 antibody SAPK 3 antibody SAPK-3 antibody SAPK3 antibody Stress Activated Protein Kinase 3 antibody Stress-activated protein kinase 3 antibody
• Abbreviation: MAPK12, ERK6, SAPK3
• CAS Number: 9000-83-3
• Swiss Prot: Q16539 Human, Q15759 Human, P53778 Human, P47811 Mouse, Q9WUI1 Mouse, O08911 Mouse, P70618 Rat, D4A3U7 Rat, Q63538 Rat
• Cellular Locus: Cytoplasm, Nucleus, Mitochondrion.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Monkey
• Immunogen: Recombinant protein within human MAPK12 aa 1-367 / 367.
• Isotype: IgG
• Clone: PSH03-60
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: 293T cell lysate, HeLa cell lysate, K-562 cell lysate, MDA-MB-231 cell lysate, COS-1 cell lysate, Neuro-2a cell lysate, PC-12 cell lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, rat heart tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 42 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes