Fibroblast Growth Factor 23 (Human, Recombinant)

• Description:

  Fibroblast Growth Factor 23 (Human, Recombinant)_x000D_ Catalog number: B2010302_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Fibroblast Growth Factor 23 (Human, Recombinant) expressed in E. coli. This protein acts as a unique FGF subfamily member that functions as as a hormone and requires α-Klotho to signal through the canonical FGFR, inducing hypertrophy and mineralization during chondrogenesis._x000D_ Storage: -20C_x000D_ Keywords: rHuFGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol._x000D_ 2001;2(3):REVIEWS3005._x000D_ _x000D_ 2: Degirolamo C, Sabbà C, Moschetta A. Therapeutic potential of the endocrine_x000D_ fibroblast growth factors FGF19, FGF21 and FGF23. Nat Rev Drug Discov. 2016_x000D_ Jan;15(1):51-69._x000D_ _x000D_ 3: Pawlikowski B, Vogler TO, Gadek K, Olwin BB. Regulation of skeletal muscle_x000D_ stem cells by fibroblast growth factors. Dev Dyn. 2017 May;246(5):359-367._x000D_ _x000D_ 4: Turner N, Grose R. Fibroblast growth factor signalling: from development to_x000D_ cancer. Nat Rev Cancer. 2010 Feb;10(2):116-29._x000D_ _x000D_ 5: Li Q, Zhai Z, Li J. Fibroblast growth factor homologous factors are potential_x000D_ ion channel modifiers associated with cardiac arrhythmias. Eur J Pharmacol. 2020_x000D_ Mar 15;871:172920._x000D_ _x000D_ 6: Thomas KA. Fibroblast growth factors. FASEB J. 1987 Dec;1(6):434-40._x000D_ _x000D_ 7: Tucker B, Li H, Long X, Rye KA, Ong KL. Fibroblast growth factor 21 in non-_x000D_ alcoholic fatty liver disease. Metabolism. 2019 Dec;101:153994._x000D_ _x000D_ 8: Su X, Kong Y, Peng D. Fibroblast growth factor 21 in lipid metabolism and_x000D_ non-alcoholic fatty liver disease. Clin Chim Acta. 2019 Nov;498:30-37._x000D_ _x000D_ 9: Terwisscha van Scheltinga AF, Bakker SC, Kahn RS, Kas MJ. Fibroblast growth_x000D_ factors in neurodevelopment and psychopathology. Neuroscientist. 2013_x000D_ Oct;19(5):479-94._x000D_ 10: Braun S, auf dem Keller U, Steiling H, Werner S. Fibroblast growth factors_x000D_ in epithelial repair and cytoprotection. Philos Trans R Soc Lond B Biol Sci._x000D_ 2004 May 29;359(1445):753-7._x000D_ _x000D_ Products Related to Fibroblast Growth Factor 23 (Human, Recombinant) : Proteins

• Short Description:

  Catalog Number: B2010302 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3