Human Fibroblast Growth Factor 18

• Description:

  Human Fibroblast Growth Factor 18_x000D_ Catalog number: B2010337_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human Fibroblast Growth Factor 18 expressed in E. coli. This protein acts as a heparin-binding polypeptide growth factor, involved in cartilage growth, maturation and the development of functional cartilage and bone tissue._x000D_ Storage: -20C_x000D_ Keywords: rHuFGF-18; zFGF5; FGF18_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Xie Y, Zinkle A, Chen L, Mohammadi M. Fibroblast growth factor signalling in_x000D_ osteoarthritis and cartilage repair. Nat Rev Rheumatol. 2020 Oct;16(10):547-564._x000D_ _x000D_ 2: Häckel S, Zolfaghar M, Du J, Hoppe S, Benneker LM, Garstka N, Peroglio M,_x000D_ Alini M, Grad S, Yayon A, Li Z. Fibrin-Hyaluronic Acid Hydrogel (RegenoGel) with_x000D_ Fibroblast Growth Factor-18 for In Vitro 3D Culture of Human and Bovine Nucleus_x000D_ Pulposus Cells. Int J Mol Sci. 2019 Oct 11;20(20):5036._x000D_ _x000D_ 3: Yu Z, Lou L, Zhao Y. Fibroblast growth factor 18 promotes the growth,_x000D_ migration and invasion of MDA‑MB‑231 cells. Oncol Rep. 2018 Aug;40(2):704-714._x000D_ _x000D_ 4: Zhang W, Robertson WB, Zhao J, Chen W, Xu J. Emerging Trend in the_x000D_ Pharmacotherapy of Osteoarthritis. Front Endocrinol (Lausanne). 2019 Jul_x000D_ 2;10:431._x000D_ _x000D_ 5: Tachmazidou I, Hatzikotoulas K, Southam L, Esparza-Gordillo J, Haberland V,_x000D_ Zheng J, Johnson T, Koprulu M, Zengini E, Steinberg J, Wilkinson JM, Bhatnagar_x000D_ S, Hoffman JD, Buchan N, Süveges D; arcOGEN Consortium, Yerges-Armstrong L,_x000D_ Smith GD, Gaunt TR, Scott RA, McCarthy LC, Zeggini E. Identification of new_x000D_ therapeutic targets for osteoarthritis through genome-wide analyses of UK_x000D_ Biobank data. Nat Genet. 2019 Feb;51(2):230-236._x000D_ _x000D_ 6: Hu MC, Wang YP, Qiu WR. Human fibroblast growth factor-18 stimulates_x000D_ fibroblast cell proliferation and is mapped to chromosome 14p11. Oncogene. 1999_x000D_ Apr 22;18(16):2635-42._x000D_ _x000D_ 7: Ellman MB, Yan D, Ahmadinia K, Chen D, An HS, Im HJ. Fibroblast growth factor_x000D_ control of cartilage homeostasis. J Cell Biochem. 2013 Apr;114(4):735-42._x000D_ _x000D_ 8: Koneczny I, Schulenburg A, Hudec X, Knöfler M, Holzmann K, Piazza G, Reynolds_x000D_ R, Valent P, Marian B. Autocrine fibroblast growth factor 18 signaling mediates_x000D_ Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. Mol_x000D_ Carcinog. 2015 Sep;54(9):789-799._x000D_ _x000D_ 9: Yamaoka H, Nishizawa S, Asawa Y, Fujihara Y, Ogasawara T, Yamaoka K, Nagata_x000D_ S, Takato T, Hoshi K. Involvement of fibroblast growth factor 18 in_x000D_ dedifferentiation of cultured human chondrocytes. Cell Prolif. 2010_x000D_ Feb;43(1):67-76._x000D_ 10: Chen T, Gong W, Tian H, Wang H, Chu S, Ma J, Yang H, Cheng J, Liu M, Li X,_x000D_ Jiang C. Fibroblast growth factor 18 promotes proliferation and migration of_x000D_ H460 cells via the ERK and p38 signaling pathways. Oncol Rep. 2017_x000D_ Feb;37(2):1235-1242. _x000D_ _x000D_ Products Related to Human Fibroblast Growth Factor 18 : Proteins

• Short Description:

  Catalog Number: B2010337 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5