Fibroblast Growth Factor-19 (Human)

• Description:

  Human Fibroblast Growth Factor-19_x000D_ Catalog number: B2010359_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human Fibroblast Growth Factor-19 expressed in E. coli. This protein acts as a protein that could activate a physiologically important, insulin-independent endocrine pathway that regulates hepatic protein and glycogen metabolism._x000D_ Storage: -20C_x000D_ Keywords: rHuFGF-19; FGF19_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Benoit B, Meugnier E, Castelli M, Chanon S, Vieille-Marchiset A, Durand C,_x000D_ Bendridi N, Pesenti S, Monternier PA, Durieux AC, Freyssenet D, Rieusset J,_x000D_ Lefai E, Vidal H, Ruzzin J. Fibroblast growth factor 19 regulates skeletal_x000D_ muscle mass and ameliorates muscle wasting in mice. Nat Med. 2017_x000D_ Aug;23(8):990-996._x000D_ _x000D_ 2: Gadaleta RM, Garcia-Irigoyen O, Cariello M, Scialpi N, Peres C, Vetrano S,_x000D_ Fiorino G, Danese S, Ko B, Luo J, Porru E, Roda A, Sabbà C, Moschetta A._x000D_ Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in_x000D_ presence of Farnesoid X Receptor. EBioMedicine. 2020 Apr;54:102719._x000D_ _x000D_ 3: Chen H, Li J, Zhang D, Zhou X, Xie J. Role of the fibroblast growth factor 19_x000D_ in the skeletal system. Life Sci. 2021 Jan 15;265:118804._x000D_ _x000D_ 4: Kim YC, Byun S, Seok S, Guo G, Xu HE, Kemper B, Kemper JK. Small Heterodimer_x000D_ Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse_x000D_ Intestine and Cholesterol Absorption. Gastroenterology. 2019_x000D_ Mar;156(4):1052-1065._x000D_ _x000D_ 5: Maeda T, Kanzaki H, Chiba T, Ao J, Kanayama K, Maruta S, Kusakabe Y, Saito T,_x000D_ Kobayashi K, Kiyono S, Nakamura M, Ogasawara S, Suzuki E, Ooka Y, Nakamoto S,_x000D_ Nakagawa R, Muroyama R, Kanda T, Maruyama H, Kato N. Serum fibroblast growth_x000D_ factor 19 serves as a potential novel biomarker for hepatocellular carcinoma._x000D_ BMC Cancer. 2019 Nov 12;19(1):1088._x000D_ _x000D_ 6: Guo A, Li K, Xiao Q. Fibroblast growth factor 19 alleviates palmitic acid-_x000D_ induced mitochondrial dysfunction and oxidative stress via the AMPK/PGC-1α_x000D_ pathway in skeletal muscle. Biochem Biophys Res Commun. 2020 Jun_x000D_ 11;526(4):1069-1076._x000D_ _x000D_ 7: Chen J, Du F, Dang Y, Li X, Qian M, Feng W, Qiao C, Fan D, Nie Y, Wu K, Xia_x000D_ L. Fibroblast Growth Factor 19-Mediated Up-regulation of SYR-Related High-_x000D_ Mobility Group Box 18 Promotes Hepatocellular Carcinoma Metastasis by_x000D_ Transactivating Fibroblast Growth Factor Receptor 4 and Fms-Related Tyrosine_x000D_ Kinase 4. Hepatology. 2020 May;71(5):1712-1731._x000D_ _x000D_ 8: Raja A, Park I, Haq F, Ahn SM. FGF19-FGFR4 Signaling in Hepatocellular_x000D_ Carcinoma. Cells. 2019 Jun 4;8(6):536._x000D_ _x000D_ 9: Rysz J, Gluba-Brzózka A, Mikhailidis DP, Banach M. Fibroblast growth factor_x000D_ 19-targeted therapies for the treatment of metabolic disease. Expert Opin_x000D_ Investig Drugs. 2015 May;24(5):603-10._x000D_ 10: Huang HH, Lee WJ, Chen SC, Chen TF, Lee SD, Chen CY. Bile Acid and_x000D_ Fibroblast Growth Factor 19 Regulation in Obese Diabetics, and Non-Alcoholic_x000D_ Fatty Liver Disease after Sleeve Gastrectomy. J Clin Med. 2019 Jun 7;8(6):815._x000D_ _x000D_ Products Related to Human Fibroblast Growth Factor-19 : Proteins

• Short Description:

  Catalog Number: B2010359 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5