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L-Glutamic acid-d5

CAT: 0804-HY-14608S7-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14608S7-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
CAS Number
2784-50-1
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.84
Solubility
H2O : 14.29 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C([2H])([2H])C([2H])([2H])[C@@](N)([2H])C(O)=O)=O
Molecular Formula
C5H4D5NO4
Molecular Weight
152.16
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
AMPA Receptor

Chemical Information

Glutamicol-d5

L-glutamic acid-d5 is a L-glutamic acid and a deuterated compound.

CAS Number2784-50-1
PubChem CID12248503
IUPAC Name(2S)-2-amino-2,3,3,4,4-pentadeuteriopentanedioic acid
Molecular FormulaC5H9NO4
Molecular Weight152.16
XLogP-3.7
Topological Polar Surface Area101
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count10
Formal Charge0
Complexity145
SMILES
[2H][C@@](C(=O)O)(C([2H])([2H])C([2H])([2H])C(=O)O)N
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i1D2,2D2,3D
InChIKey
WHUUTDBJXJRKMK-NKXUJHECSA-N
Chemical Structure
2D Structure
2D structure of Glutamicol-d5
CAS: 2784-50-1
CID: 12248503
Formula: C5H9NO4
MW: 152.16
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight152.16
XLogP3-3.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass152.08454150
Monoisotopic Mass152.08454150
Topological Polar Surface Area101 Ų
Heavy Atom Count10
Formal Charge0
Complexity145
Isotope Atom Count5
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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