L-Glutamic acid-13C5,15N,d5

• UNSPSC Description:

  L-Glutamic acid-13C5,15N,d5 is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

• Target Antigen:

  Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Purity:

  99.0

• Solubility:

  DMSO : 6.25 mg/mL (ultrasonic;warming)|H2O : ＜1 mg/mL (ultrasonic;warming)

• Smiles:

  O[13C]([13C]([2H])([2H])[13C]([2H])([2H])[13C@@]([15NH2])([2H])[13C](O)=O)=O

• Molecular Weight:

  158.12

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1420815-74-2