Sanggenol A

• Description:

  Sanggenol A acts as a dual inhibitor of nitrofuranone reduction mediated by the intestinal microbial nitrification reductases EcNfsA and EcNfsB. In addition, Sanggenol A is also an effective inhibitor of intestinal bacterial β-glucuronidase[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Bacterial; β-glucuronidase

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/sanggenol-a.html

• Purity:

  99.83

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C[C@@H] (C2=CC=C (O) C (C/C=C (C) /CC/C=C (C) \C) =C2O) OC3=CC (O) =CC (O) =C13

• Molecular Formula:

  C25H28O6

• Molecular Weight:

  424.49

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Xi Chen, et al. Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases. Chem Biol Interact. 2022 Dec 1;368:110222.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  174423-30-4