Products for Research Use Only
RegisterLogin

Sanggenon C

CAT: 0804-HY-N0617-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0617-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-α-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities[1][2].
CAS Number
80651-76-9
UNSPSC
12352005
Target
Apoptosis; ERK; NF-κB; Phosphatase
Type
Natural Products
Related Pathways
Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sanggenon-c.html
Purity
98.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(C)=C/C[C@](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([C@@H](C=C(C)C[C@@H]4C(C=CC(O)=C5)=C5O)[C@@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[C@]27O
Molecular Formula
C40H36O12
Molecular Weight
708.71
References & Citations
[1]Xiao L, et al. Sanggenon C protects against pressure overload induced cardiac hypertrophy via the calcineurin/NFAT2 pathway. Mol Med Rep. 2017 Oct;16 (4) :5338-5346.|[2]Xiao-Jie Chen, et al. Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission. J Nat Prod. 2022 Oct 28;85 (10) :2351-2362.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERK; NF-κB

Related Products

CatalogName
HY-N11657-01Sanggenon A
HY-N13160Sanggenon F
HY-N0618-01Sanggenon D
HY-12372-01Sanggenon G
HY-N5154-01Sanggenon W
HY-N16172Sanggenon B
HY-N8836Sanggenon K
HY-N1324-01Sanggenon N
HY-N12810-01Sanggenon O
HY-N1322-01Sanggenol A

Alternative Products

CatalogName
GTR19230128Sanggenon A
300919Sanggenon C
MBS5787333Sanggenon N
MBS5791966Sanggenon O
BUP01394-01Sanggenon D
GTR19233554-01Sanggenon W
TN8172-01Sanggenon F
MBS5815931Sanggenon G
T124180-01Sanggenon B

Popular Products