Products for Research Use Only
RegisterLogin

CH 5450

CAT: 0804-HY-16707-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-16707-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM[1].
CAS Number
252557-97-4
Product Name Alternative
Z-Ile-Glu-Pro-Phe-Ome
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Proteasome
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Z-Ile-Glu-Pro-Phe-Ome.html
Purity
98.19
Solubility
DMSO : ≥ 43 mg/mL
Smiles
O=C(OC)[C@@H](NC([C@H]1N(C([C@@H](NC([C@@H](NC(OCC2=CC=CC=C2)=O)[C@@H](C)CC)=O)CCC(O)=O)=O)CCC1)=O)CC3=CC=CC=C3
Molecular Formula
C34H44N4O9
Molecular Weight
652.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Carlos F Santos, et al. Kinetic characterization and inhibition of the rat MAB elastase-2, an angiotensin I-converting serine protease. Can J Physiol Pharmacol. 2002 Jan;80 (1) :42-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-163235Phenyl phenylcarbamate-CH-5-methoxypicolinamide-CH-CH-Ph-CF3
HY-122894Ch-319
HY-12684-01CH-223191
HY-W728163CH-PIATA
HY-172867CH-HEXIATA
HY-170720-01CH-FUBIATA
HY-126036CH-141
HY-113713CH-38083
HY-P1206-01CH 275
HY-131675CH-100

Alternative Products

CatalogName
TP1012-01CH 5450
A21974-200CH 5450 200mg
A21974-5CH 5450 5mg
A21974-1CH 5450 1mg
A21974-100CH 5450 100mg
A21974-25CH 5450 25mg
50189-1PCL-5450 Cartridge
A21974-50CH 5450 50mg
A21974-10CH 5450 10mg
A21974-10mM-DCH 5450 10mM * 1mL in DMSO

Popular Products