2'-O,4'-C-Methyleneadenosine

2'-O,4'-C-Methyleneadenosine

• CAS Number: 206055-70-1
• UNSPSC Description: 2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].
• Target Antigen: DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/2-o-4-c-methyleneadenosine.html
• Purity: 96.96
• Solubility: 10 mM in DMSO
• Smiles: OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C(N=CN=C4N)=C4N=C3)O1
• Molecular Weight: 279.256
• References & Citations: [1]Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported