2'-O,4'-C-Methylenecytidine

• UNSPSC Description:

  2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-o-4-c-methylenecytidine.html

• Purity:

  98.59

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C=CC(N)=NC3=O)O1

• Molecular Weight:

  255.23

• References & Citations:

  [1]bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes|[2]Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  206055-69-8