2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium)

CAT:

804-HY-154159

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UNSPSC Description: 2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/2-o-4-c-methyleneadenosine-5-monophosphate-triethylammonium.html
Solubility: 10 mM in DMSO
Smiles: O[C@@H]1[C@@]2(COP(O)(O)=O)O[C@H]([C@]1([H])OC2)C3=NC4C(N=CN=C4N)N3.CCN(CC)CC.CCN(CC)CC
Molecular Weight: 563.63
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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