Products for Research Use Only
RegisterLogin

LOXL4 rabbit pAb

CAT: 0855-ES15131-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES15131-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008],
UniProt
Q96JB6
Swiss Prot
Q96JB6
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human LOXL4 AA range: 39-89
Target
LOXL4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted, extracellular space .
Gene ID (Human)
84171

UniProtKB · Q96JB6

Lysyl oxidase homolog 4

LOXL4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96JB6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LOXL4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.4.3.13
Processing
Precursor
Secondary accessions
Q5W0B3, Q96DY1, Q96PC0, Q9H6T5
Protein keywords

Ligand

CopperMetal-binding

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinLTQTPQ

Molecular function

Oxidoreductase

Domain

RepeatSignal

Cellular component

Secreted

Related Products

CatalogName
ES15132-01LOXL3 rabbit pAb
ES11072-01LOXL2 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8600743-01LOXL4 rabbit pAb
GTR17875657LOXL4 Rabbit Polyclonal Antibody
GB111854-50Anti-LOXL4 Rabbit pAb
P34521-01Rabbit Polyclonal Antibody to LOXL4
NBP3-04898-20ulRabbit Polyclonal LOXL4 Antibody
GTR18402771-01LOXL4 rabbit pAb Antibody
SL5790R-01Rabbit Anti-LOXL4 antibody
567441-01Loxl4

Popular Products