Products for Research Use Only
RegisterLogin

(R) -DPN

CAT: 0804-HY-103453Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-103453Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(R) -DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R) -DPN shows a very high affinity and potency preference for ERβ over ERα. (R) -DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1].
CAS Number
524047-78-7
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/r-dpn.html
Solubility
10 mM in DMSO
Smiles
N#C[C@@H](C(C=C1)=CC=C1O)CC(C=C2)=CC=C2O
Molecular Formula
C15H13NO2
Molecular Weight
239.27
References & Citations
[1]Carroll VM, et al. Diarylpropionitrile (DPN) enantiomers: synthesis and evaluation of estrogen receptor β-selective ligands. J Med Chem. 2012 Jan 12;55 (1) :528-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα; ERβ

Related Products

CatalogName
HY-12452-01DPN
HY-KE7011Dpn I
HY-12452R-01DPN (Standard)
HY-KE7012Dpn II
HY-19089DPN-205-734
HY-W998245(R, R, R) -AHPC (hydrochloride)
HY-W018061C-01(R, R) -Traxoprodil
HY-103451(R, R) -THC
HY-128888-01(R, R) -GSK321
HY-113834(R, R) -Ethambutol

Alternative Products

CatalogName
B6763-100DPN
K1104-5000Dpn I
256417(R) -DPN
A21446-50DPN 50mg
MBS5757689(R)-DPN
6028050Dpn II
GTR17968303Dpn Antibody
A21446-5DPN 5mg
C12231-25mgDiarylpropionitrile (DPN)

Popular Products