Casein Kinase 1 alpha Recombinant Rabbit Monoclonal Antibody [PSH04-46]

Casein Kinase 1 alpha Recombinant Rabbit Monoclonal Antibody [PSH04-46]

• Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3 (By similarity).
• Product Name Alternative: Casein kinase 1 alpha 1 antibody Casein kinase I isoform alpha antibody CK1 antibody CK1A antibody CKI alpha antibody CKI-alpha antibody CKIa antibody Clock regulator kinase antibody Csnk1a1 antibody Down regulated in lung cancer antibody HLCDGP1 antibody KC1A_HUMAN antibody PRO2975 antibody
• Abbreviation: CSNK1A1
• CAS Number: 9000-83-3
• Swiss Prot: P48729 Human, Q8BK63 Mouse, P97633 Rat
• Cellular Locus: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Nucleus speckle, cilium basal body, spindle.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human CSNK1A1 aa 1-337 / 337.
• Isotype: IgG
• Clone: PSH04-46
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, FC, IP
• Positive Control: HCT 116 cell lysate, HeLa cell lysate, HEK-293 cell lysate, MCF7 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, HCT 116.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IF-Cell: 1:500 ;FC: 1:1,000 ;IP: 1-2μg/sample
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 39 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes