Adenosine-15N

CAT: 0804-HY-W779021-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W779021-01Size:5 mg
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Description
Adenosine-15N (Adenine riboside-15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].
CAS Number
[41547-82-4]
Product Name Alternative
Adenine riboside-15N; D-Adenosine-15N
UNSPSC
12352005
Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Smiles
O[C@H]1[C@H]([C@@H](O[C@@H]1CO)N2C3=C(N=C2)C([15NH2])=NC=N3)O
Molecular Formula
C10H13N4 15NO4
Molecular Weight
268.23
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98 (3) :1591-1625.|[3]Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ. 2007;14 (7) :1315-1323.|[4]Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41 (2) :829-838.|[5]Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111 (4) :904-915.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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