Login

PDK1-IN-RS2

CAT:
804-HY-114645-06
Size:
100 mg
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PDK1-IN-RS2 - image 1

PDK1-IN-RS2

  • CAS Number: 1643958-89-7
  • UNSPSC Description: PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a Kd of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1[1].
  • Target Antigen: PDK-1
  • Type: Reference compound
  • Related Pathways: PI3K/Akt/mTOR
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/pdk1-in-rs2.html
  • Purity: 98.50
  • Solubility: DMSO : 125 mg/mL (ultrasonic)
  • Smiles: O=S(C1=CC2=CC=CC=C2S1)(NC3=NC4=CC=C(C=C4S3)Cl)=O
  • Molecular Weight: 380.89
  • References & Citations: [1]Rettenmaier TJ, et al. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5.
  • Shipping Conditions: Blue Ice
  • Storage Conditions: -20°C, 3 years (Powder)
  • Clinical Information: No Development Reported