PLAUR Antibody (C-term) [APR04624G]

• Background:

  Tissue Location: Expressed in neurons of the rolandic area of the brain (at protein level) . Expressed in the brain

• Synonyms:

  Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR

• Gene Name:

  PLAUR

• Gene ID:

  5329

• UniProt:

  Q03405

• Chromosomal Location:

  Cell membrane. Cell projection, invadopodium membrane Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin- dependent manner. [Isoform 2]: Secreted {ECO:0000250|UniProtKB:P49616}

• Applications:

  WB, IHC-P

• Dilution:

  IHC-P--1:100~500 WB--1:1000

• Function:

  Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

• Molecular Weight:

  36978

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLAUR Antibody (C-term) [APR04624G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5329

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q03405