Cyclin A (CCNA2) Antibody (N-term) [APR05876G]

• Synonyms:

  Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA

• Gene Name:

  HGNC:1578

• Gene ID:

  890

• UniProt:

  P20248

• Chromosomal Location:

  Nucleus. Cytoplasm. Note=Exclusively nuclear during interphase (PubMed:1312467) . Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467) . Cytoplasmic when associated with SCAPER (PubMed:17698606) .

• Applications:

  IHC-P, FC, WB

• Dilution:

  WB--1:2000 IHC-P--1:100~500 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin- dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.

• Molecular Weight:

  48551

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cyclin A (CCNA2) Antibody (N-term) [APR05876G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=890

• Uniprot URL:

  https://www.uniprot.org/uniprot/P20248