SGK1-IN-4

SGK1-IN-4

• CAS Number: 1628048-93-0
• UNSPSC Description: SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research[1].
• Target Antigen: SGK
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/sgk1-in-4.html
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: O=S(NC(C=C1)=CC=C1C2=NC(O[C@@H]3CC[C@H](CC3)O)=C4C(NN=C4)=N2)(C5=C(C=CC(Cl)=C5)F)=O
• Molecular Weight: 517.96
• References & Citations: [1]Nis Halland, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022 Jan 27;65(2):1567-1584.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported