SGK1-IN-1

SGK1-IN-1

• CAS Number: 1279829-87-6
• UNSPSC Description: SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM.
• Target Antigen: SGK
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/SGK1-IN-1.html
• Purity: 99.67
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=S(C1=C(F)C=CC(Cl)=C1)(NC2=CC=C(C3=NC(NN=C4N)=C4N=C3)C=C2)=O
• Molecular Weight: 418.83
• References & Citations: [1]ARYL SULFONOHYDRAZIDES. WO 2013041119 A1.|[2]Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported