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SGK1-IN-3

CAT: 0804-HY-142686Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142686Size:1 Each
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Description
SGK1-IN-3 (compound 3a) is a potent SGK1 inhibitor with an IC50 of [1].
CAS Number
2891696-18-5
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sgk1-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=CC=C(C=C2)NS(=O)(C3=C(C(Cl)=CC=C3)Cl)=O)=NC4=C1C=NN4)N[C@@H]5CCNC5
Molecular Formula
C23H20Cl2N6O3S
Molecular Weight
531.41
References & Citations
[1]Halland N, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022;65 (2) :1567-1584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGK1

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