(Mouse) Lin28a Antibody (C-term) [AMM08714G]

• Background:

  Tissue Location: Expressed in embryonic stem cells (ES cells), spermatagonia and testis. Expressed in numerous epithelial tissues including the epithelia of the small intestine, the intralobular duct epithelium of the mammary gland and the epithelia of Henle's loop in the kidney and in the collecting duct (at protein level) . Also expressed in the myocardium and skeletal muscle (at protein level)

• Synonyms:

  Protein lin-28 homolog A, Lin-28A, Testis-expressed protein 17, Lin28a, Lin28, Tex17

• Gene Name:

  Lin28a

• Gene ID:

  83557

• UniProt:

  Q8K3Y3

• Chromosomal Location:

  Cytoplasm. Rough endoplasmic reticulum. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9H9Z2}. Cytoplasm, Stress granule. Nucleus, nucleolus. Note=Predominantly cytoplasmic (PubMed:12798299) . In the cytoplasm, localizes to peri-endoplasmic reticulum regions and detected in the microsomal fraction derived from rough endoplasmic reticulum (RER) following subcellular fractionation May be bound to the cytosolic surface of RER on which ER-associated mRNAs are translated (PubMed:23102813) . Shuttle from the nucleus to the cytoplasm requires RNA-binding (PubMed:17473174) . Nucleolar localization observed in 10-15% of the nuclei in differentiated myotubes (PubMed:17473174) .

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  17473174186041951856619118292307197033962310281324209617260455591747317419703396286716662310281324209617

• Molecular Weight:

  22720

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (Mouse) Lin28a Antibody (C-term) [AMM08714G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=83557

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8K3Y3