LIN28A Antibody [AMM06300G]

• Background:

  Tissue Location: Expressed in embryonic stem cells, placenta and testis. Tends to be up-regulated in HER2-overexpressing breast tumors

• Synonyms:

  Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1

• Gene Name:

  LIN28A

• Gene ID:

  79727

• UniProt:

  Q9H9Z2

• Chromosomal Location:

  Cytoplasm. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:Q8K3Y3}. Cytoplasm, P-body. Cytoplasm, Stress granule. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8K3Y3}. Note=Predominantly cytoplasmic (PubMed:22118463) . In the cytoplasm, localizes to peri-endoplasmic reticulum regions and detected in the microsomal fraction derived from rough endoplasmic reticulum (RER) following subcellular fractionation May be bound to the cytosolic surface of RER on which ER-associated mRNAs are translated (By similarity) . Shuttle from the nucleus to the cytoplasm requires RNA-binding (PubMed:17617744) . Nucleolar localization is observed in 10-15% of the nuclei in differentiated myotubes (By similarity) . {ECO:0000250|UniProtKB:Q8K3Y3, ECO:0000269|PubMed:17617744, ECO:0000269|PubMed:22118463}

• Applications:

  WB, IHC-P, IF

• Dilution:

  WB--1:200~2000 IHC-P--1:100~500 IF--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  2124787618951094197033962211846322898984

• Molecular Weight:

  22743

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIN28A Antibody [AMM06300G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=79727

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H9Z2