Biotin-PFP ester

• Description:

  Biotin-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/biotin-pfp-ester.html

• Purity:

  98.51

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C1N[C@]2 (CS[C@H] ([C@]2 (N1) [H]) CCCCC (OC3=C (C (F) =C (C (F) =C3F) F) F) =O) [H]

• Molecular Formula:

  C16H15F5N2O3S

• Molecular Weight:

  410.36

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers

• CAS Number:

  120550-35-8