Biotin-PEG4-PFP ester

• Description :

  Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• CAS Number :

  [1334172-58-5]

• UNSPSC :

  12352203

• Hazard Statement :

  H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/biotin-peg4-pfp-ester.html

• Purity :

  96.18

• Solubility :

  10 mM in DMSO

• Smiles :

  C(CCCC(NCCOCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O)=O)[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H]

• Molecular Formula :

  C27H36F5N3O8S

• Molecular Weight :

  657.65

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Cleavable Linker