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Euptox A

CAT: 0804-HY-N2802Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N2802Size:1 Each
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Description
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells[1].
CAS Number
79491-71-7
Product Name Alternative
9-Oxo-10,11-dehydroageraphorone
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Caspase; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/euptox-a.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C1[C@@]2([H])[C@@](CC(C(C)=C2)=O)([H])[C@@H](C)CC/1=O
Molecular Formula
C15H20O2
Molecular Weight
232.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Liao F, et al. Induction and mechanism of HeLa cell apoptosis by 9-oxo‑10, 11-dehydroageraphorone from Eupatorium adenophorum. Oncol Rep. 2015 Apr;33 (4) :1823-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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