Euphol acetate

• Description:

  Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3) [1][2].

• UNSPSC:

  12352211

• Target:

  OAT

• Type:

  Natural Products

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/euphol-acetate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]([C@]12C)(CC[C@@]1([H])[C@H](C)CC/C=C(C)\C)C(CC[C@@]3([H])C4(C)C)=C(CC2)[C@]3(CC[C@@H]4OC(C)=O)C

• Molecular Formula:

  C32H52O2

• Molecular Weight:

  468.75

• References & Citations:

  [1]DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26 (6) : 1767-1776.|[2]Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83 (6) :1257-67.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [13879-04-4]