Euphol acetate

• Description :

  Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3) [1][2].

• UNSPSC :

  12352211

• Target :

  OAT

• Type :

  Natural Products

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/euphol-acetate.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]([C@]12C)(CC[C@@]1([H])[C@H](C)CC/C=C(C)\C)C(CC[C@@]3([H])C4(C)C)=C(CC2)[C@]3(CC[C@@H]4OC(C)=O)C

• Molecular Formula :

  C32H52O2

• Molecular Weight :

  468.75

• References & Citations :

  [1]DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26 (6) : 1767-1776.|[2]Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83 (6) :1257-67.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [13879-04-4]