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Euphol (Standard)

CAT: 0804-HY-N0313R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0313R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Euphol (Standard) is the analytical standard of Euphol. This product is intended for research and analytical applications. Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM) . MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain[1].
CAS Number
514-47-6
UNSPSC
12352100
Target
Endogenous Metabolite; MAGL; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
C[C@@]1(CC2)[C@@](CC[C@]1([C@H](C)CC/C=C(C)/C)[H])(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](O)CC4
Molecular Formula
C30H50O
Molecular Weight
426.72
References & Citations
[1]Dutra RC, et al. Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system. Neuropharmacology. 2012 Sep;63 (4) :593-605.|[2]Wang L, et al. Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression. Mol Med Rep. 2013 Oct;8 (4) :1279-85.|[3]Wang L, et al. Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression. Mol Med Rep. 2013 Oct;8 (4) :1279-85.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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