Anti-Hu CD231 PE-Cy1537

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Alternative Products

Cat	Name
MBS1800376-01	Anti-Hu CD231 PE
MBS1800376-02	Anti-Hu CD231 PE
MBS1800377-02	Anti-Hu CD231 PE-Cyanine7
MBS1800377-01	Anti-Hu CD231 PE-Cyanine7
MBS1800374-01	Anti-Hu CD231 APC
MBS1800373-02	Anti-Hu CD231 Purified
MBS1800374-02	Anti-Hu CD231 APC
MBS1800373-01	Anti-Hu CD231 Purified
MBS1800375-01	Anti-Hu CD231 FITC
MBS1800375-02	Anti-Hu CD231 FITC

CAT:

270-T7-200-T100

Size:

100 Tests

Price:

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Anti-Hu CD231 PE-Cy1537

Background: CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington´s chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.
Specifications: The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.
Certification: RUO
Host: Mouse
Species Reactivity: Human
Immunogen: Human T-ALL cell line THP-6
Target Antigen: CD231
Isotype: IgG1
Clone: B2D
Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.
Validated Applications: FC
Format: PE-Cy1537
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations: *Takagi S, Fujikawa K, Imai T, Fukuhara N, Fukudome K, Minegishi M, Tsuchiya S, Konno T, Hinuma Y, Yoshie O: Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily. Int J Cancer. 1995 May 2961(5):706-15., URL: https://www.ncbi.nlm.nih.gov/pubmed/7768645,
Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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