Anti-Hu Ig Lambda Light Chain PE

CAT: 0270-1P-505-T100Size: 100 TestsDry Ice: NoHazardous: No
CAT#:0270-1P-505-T100Size:100 Tests
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa) . Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Certification
RUO
Negative Species
Rabbit, Hamster, Sheep, Guinea pig, Goat
Reactivity
Human
Target Antigen
Ig Lambda Light Chain
Clone
4C2
Applications
FC (QC tested)
Format
PE
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjø nnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4 (3) :566-77., URL: https://www.ncbi.nlm.nih.gov/pubmed/23933259
Other References
*Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh) . 1975;194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.
Applications Notes
6
Isotype
Mouse IgG1

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