Cidofovir diphosphate tri(triethylamine)

Cidofovir diphosphate tri(triethylamine)

• UNSPSC Description: Cidofovir diphosphate tri triethylamine is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate tri triethylamine is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cidofovir-diphosphate-tri-triethylamine.html
• Purity: 99.39
• Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : 125 mg/mL (ultrasonic)
• Smiles: O=P(O)(O)OP(OP(CO[C@H](CO)CN1C(N=C(C=C1)N)=O)(O)=O)(O)=O.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC
• Molecular Weight: 742.72
• References & Citations: [1]Hitchcock MJM, et al. Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity. 1996.|[2]Magee WC, et al. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother. 2005 Aug;49(8):3153-62.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported